Osteoarthritis is a leading cause of disability worldwide — a debilitating
disease that limits movement and causes pain in the joints of the knees,
hips, and hands.
Hand osteoarthritis affects millions of people and is much more common in
women than in men. Recently, a study proposed mechano inflammation as the
primary driver of hand osteoarthritis and identified the importance of
retinoic acid in its development.
The research team showed the drug talarozole boosts the levels of retinoic
acid in the joint, suppressing mechano inflammation — potentially modifying
the course of the disease.
Osteoarthritis(OA) is a degenerative disease of the joints that commonly
affects the knees, hips, and hands. It is a chronic condition that affects
over 32.5 millionTrusted Source adults in the United States.The cause of OA is not entirely understood, but it happens when cartilage —
the smooth, slippery, cushioned surface covering the ends of bones — bre.
disease that limits movement and causes pain in the joints of the knees,
hips, and hands.
Hand osteoarthritis affects millions of people and is much more common in
women than in men. Recently, a study proposed mechano inflammation as the
primary driver of hand osteoarthritis and identified the importance of
retinoic acid in its development.
The research team showed the drug talarozole boosts the levels of retinoic
acid in the joint, suppressing mechano inflammation — potentially modifying
the course of the disease.
Osteoarthritis(OA) is a degenerative disease of the joints that commonly
affects the knees, hips, and hands. It is a chronic condition that affects
over 32.5 millionTrusted Source adults in the United States.The cause of OA is not entirely understood, but it happens when cartilage —
the smooth, slippery, cushioned surface covering the ends of bones — bre.