A recent study published in Cardiovascular Research suggests that
LAV-BPIFB4, a gene variant that previous research ha shown to be highly
expressed by individuals with an exceptionally long lifespan, could also
protect cardiac and vascular function in old age.Studies have shown that the longevity-associated variant (LAV) of the
BPIFB4 gene is associated with a longer lifespan in humans and has
protective effects in rodent models of cardiovascular disease.A new study shows that LAV-BPIFB4 may exert its cardioprotective effects by
promoting the formation of new blood vessels and reducing the number of
blood vessel cells that have become senescent and stopped multiplying.
LAV-BPIFB4, a gene variant that previous research ha shown to be highly
expressed by individuals with an exceptionally long lifespan, could also
protect cardiac and vascular function in old age.Studies have shown that the longevity-associated variant (LAV) of the
BPIFB4 gene is associated with a longer lifespan in humans and has
protective effects in rodent models of cardiovascular disease.A new study shows that LAV-BPIFB4 may exert its cardioprotective effects by
promoting the formation of new blood vessels and reducing the number of
blood vessel cells that have become senescent and stopped multiplying.
The study indicates that inducing the expression of LAV-BPIFB4 in aged mice
improved cardiac function and regulation of blood flow to the heart.
These findings highlight the therapeutic potential of LAV-BPIFB4 for
attenuating the adverse .
